In Germany, a type-2 diabetes is often treated with tablets. These are relatively easy to handle and do not require intensive training as they are common for insulin users. Nevertheless, type-2 diabetes have a relatively high risk for atherosclerosis and heart disease. A new study has dealt with the question of which treatment option for type 2 diabetes cheap.
In contrast to the insulin-dependent type 1 diabetes produce humans with type 2 diabetes, even a small amount of endogenous insulin. This amount is often small, that they no longer sufficient to adequately regulate the blood sugar. In addition, the metabolism of a type-2 diabetics often speaks to the existing insulin significantly less responsive than in perfectly healthy people would be the case. In this problem, so-called “oral agents” to correct the situation. These tablets increase the effects of the existing residual insulin and stimulate the pancreas to pour out to, for example at meals sufficient endogenous insulin. In the tablets even no insulin is included because it would be destroyed by stomach acid. In Germany, a type-2 diabetes is usually treated with oral antidiabetic agents. Only when the excess of regular long-term blood sugar levels (HbA1c), despite all efforts, the level of 7% are type 2 diabetics treated with insulin.
Texas study examines the advantages and disadvantages of diabetes therapy
A team of endocrinologists in the United States had now for three years, recently published study examined the self-treatment of people with type 2 diabetes. The study involved about 58 people had taken part with a newly diagnosed diabetes who were assigned randomly to one of two groups. One group was treated during the three-year observation period with insulin and the drug metformin, the other group received a combination treatment with the antidiabetic metformin, pioglitazone, and glyburide.
Insulin and combination tablets are equally good
The result: The HbA1c of both groups differed at the end of the study, only 0.1 percent. The insulin group had reached an average of 6.1%, the tablet group had the slightly better value of 6%. Weight gain was observed in both groups. Surprisingly, participants had risen kg in the insulin group, however, only about 4.5, while the tablet group average of 7.2 kg with a lot more put on the scales. Hypoglycemia occurred during the study in both groups rarely, and usually, these were not severe hypoglycemia. The self-discipline and the satisfaction with the therapy in both groups were also roughly equal.
Results are not fully meaningful
As a result, the insulin / metformin therapy and the combination of three anti-diabetic agents also equal. However, a combination of three different anti-diabetic agents in Germany is practiced only in emergencies, because the blood glucose in most patients even with a tablet can be adjusted very well. In addition, a study with only 60 patients compared to the experience of millions of diabetics is not meaningful.
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Tags: diabetes, Diabetes Therapy, diabetes treatment, diabetes type II, drugs, early insulin therapy, insulin, insulin therapy, medicine, tablets