Diabetes Treatment Weblog

Posts Tagged ‘diabetes type I’

A new vaccine to protect children with low glucose tolerance before an impending type 1 diabetes. Whether this is really possible, is now finally prove, inter alia, a study of the Technical University of Munich.

A type-1 diabetes develops when the immune system attacks a bad reaction in one’s own pancreas and destroys the insulin-producing cells. Due to an inflammatory reaction, which takes different lengths, the pancreas can no longer fulfill their function and diabetes becomes apparent. The onset of diabetes may last, depending on the injury, so that even ill babies or adults only. How it but at the slip of the immune system, so the exact cause of diabetes, occurs remains unclear.

Vaccination against type 1 diabetes?
If several relatives of a child have type 1 diabetes are affected, the genetic risk for the child greatly increases also suffer from diabetes too. Now by contrast, could potentially help the early administration of small doses of insulin as a kind of vaccination. Unlike type-1-Diabektikern with overt diabetes, the insulin for at-risk children do not serve to lower their blood sugar. It affects the immune system and prevent the fatal bad reaction to the pancreas in the long run. Two studies will now investigate in Austria, Italy, Britain, Canada, the USA and in Germany, how much insulin is suitable for the prevention and how it needs to be taken. The hormone could for example be administered in very small doses by mouth or as a nasal spray. When taken orally, insulin has no blood glucose-lowering effect, because it is ineffective by the stomach acid. With the hormone only children should be treated, although they are burdened with a high hereditary risk of diabetes, but still show no symptoms of the disease.

Who can participate in the prevention trial?
In Germany, experimental subjects aged 18 months to 7 years to be searched, where a family history is given with diabetes. Notes for a high risk of disease include pre-existing diabetes type 1 disease among siblings or their own parents. Before study participation, the individual risk of diabetes of the participating child is determined. The examinations and treatments during the studies are free of charge to participating families. The study is supported by the German Federal Ministry for Education and Research and the American Foundation for Diabetes Study. The study is called “pre-point” and is conducted in Germany by Professor Ezio Bonifacio at the TU Munich. For the 18-month study will be looking for a total of 40 children.

Diabetes is a disease that may have people of all ages (currently affects almost 220 million human beings in the world, said months ago this health blog). Then there will be a newspaper article about what there is to know about diabetes.

Diabetes is defined as a metabolic disorder that involves having blood glucose (sugar) levels above the levels set. Is taken as normal blood levels between 70 and 100 mg / dl fasting. When levels exceed these values, in chronic form begins with lesions in organs like the heart, eyes, kidneys, nerves, feet and blood vessels.

Importantly, there are different types of diabetes: Type 1 diabetes is characterized by the absence of synthesis of insulin in type 2 diabetes which has its origin in the body’s inability to effectively use the insulin (the most common and can be prevented) and the so-called “gestational diabetes” which was first discovered during the stage of pregnancy.

In another vein, it is necessary to add that there are certain factors that are associated with diabetes, obesity, stress, poor diet, family history and / or hypertension.

People with diabetes may reduce these risk factors and live a normal life. For this, you must acquire some patterns of behavior such as physical exercise, a controlled medication, a balanced diet as well as having a regular medical checks.

Explains research materials for the realization of this note, which was compiled by the website Cardiosalud.org, patients with this disease can achieve a good quality of life depending on the habits they acquire.

It is important to add that this disease affects about 220 million people, according to official figures published on the website of the World Health Organization (WHO) on the occasion of World Diabetes Day, which were published months ago in this blog.

Alice Posada has marked in her memory December 26, 2006, the day they discovered that her daughter Emily had diabetes type I, a metabolic disease that requires daily insulin injections.

Her daughter, then 18-months old, was rushed and spent several days in the hospital tested until doctors were able to determine the dose of insulin needed to balance your blood sugar level. “I do not understand anything, it was blank,” said Alice to voanoticias.com, who until now had no close relative with Type I diabetes

Hospital Alice and her husband came up with an idea of how the metabolism of Emilia, what dose of insulin would need daily, what kind of diet should continue and at what times I had to eat. In practice, this meant a total rethinking of their lives. Alice had to leave her job of 10 years as a clerk in a blood bank to provide care for her daughter. And over the years, she and her family learned to overcome their fears and prepare for future obstacles.

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Free screenings for diabetes will be offered on Saturday August 7 from 9 am 2 p.m. Diabetes Expo at the “Health and Welfare” to be held at the Convention Center Hotel Holiday Inn in Springdale.

Do not ask for ID and is free, said Krista Coffee, deputy director of the Northwest Arkansas office of the American Diabetes Association (ADA for its acronym in English).

Spanish translators will be 12 and there will be information available in English and Spanish, said Lori Bramlett, regional director of ADA.

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There are two types of diabetes. In type 1 diabetes, which usually starts in childhood, the pancreas stops producing insulin altogether. It is also called insulin-dependent diabetes. In type 2 diabetes, which begins in adulthood (and in some teenagers) the body still produces some insulin.

But do not make enough insulin or the body can not use it properly. It is also known as noninsulin-dependent diabetes.

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The self refers to being capable of self blood glucose checked at home. Also called self-monitoring of blood glucose (SMBG by its acronym in English). Regular self-testing blood sugar tells you and your doctor how well is working diet, exercise and medication for diabetes.

A device called a glucometer can provide an exact blood sugar reading. There are different types of devices. Usually, you prick your finger with a small needle called a lancet to get a tiny drop of blood. You place the blood onto a test strip and put the strip on the device. Results are available within 30 to 45 seconds.

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The first human trials of the latest design of an artificial pancreas for people with type 1 diabetes found that the drive works without causing low blood sugar (hypoglycemia).
In the best case, this type of automated device finally released people with type 1 diabetes need injections that many each day and the constant need to check levels of blood sugar and monitor their food as appropriate.

The device, produced through a collaboration of experts from Boston University, Massachusetts General Hospital and Harvard Medical School has two hormones that are deficient among Type 1 diabetic, insulin, which prevents levels blood sugar get too high after a meal, and glucagon, a hormone that occurs naturally that prevents blood sugar levels fall too far.

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The physical health of people with serious mental illnesses such as schizophrenia or bipolar disorder is worse than that of the healthy population. People affected by this group of diseases have an increased cardiovascular mortality, attributed to a risk from 1 to 5 times higher than present modifiable coronary risk factors such as obesity, smoking, diabetes, hypertension and dyslipidemia. Specifically, in the case of schizophrenia life expectancy is shortened by up to ten years.

This is one of the main conclusions of consensus “Cardiovascular disease and diabetes in people with severe mental illness, which in Spain is supported by the Spanish Society of Biological Psychiatry, together with the Spanish Society of Psychiatry, the Spanish Society of Diabetes and Spanish Society of Cardiology.

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An experimental vaccine that contains tiny particles of an immune system protein was able to reverse type 1 diabetes in mice, a finding that could be applied to humans, say Canadian researchers.

Type 1 diabetes occurs when certain white blood cells called T-cells go haywire and start attacking the insulin-producing cells in the pancreas.

But not all T cells are harmless, said Dr. Pere Santamaria, of the University of Calgary in Alberta, whose study was published in the journal Immunity.

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