Diabetes Treatment Weblog

Posts Tagged ‘insulin’

The first human trials of the latest design of an artificial pancreas for people with type 1 diabetes found that the drive works without causing low blood sugar (hypoglycemia).
In the best case, this type of automated device finally released people with type 1 diabetes need injections that many each day and the constant need to check levels of blood sugar and monitor their food as appropriate.

The device, produced through a collaboration of experts from Boston University, Massachusetts General Hospital and Harvard Medical School has two hormones that are deficient among Type 1 diabetic, insulin, which prevents levels blood sugar get too high after a meal, and glucagon, a hormone that occurs naturally that prevents blood sugar levels fall too far.

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Researchers at the National University Hospital in Taiwan today reported new diabetes treatments through bypass surgery and gastric narrowing.

The Taiwanese doctors presented at a press conference the positive results of therapy in 60 cases of operated diabetic gastric surgery over a year ago.

Diabetes is really a gastrointestinal disease, resulting from problems with the gastrointestinal hormones that influence insulin production, so it can be treated with gastric surgery,” said a spokesman for the doctors, Li Wei-jie.

In an experiment with 60 patients, average age 45 years, found that one year after gastric bypass surgery, 93.3 percent had normal blood sugar level and in the case of gastric narrowing, the proportion was 46.7 percent.

Researchers at the Taiwan Normal University said that with current therapies and medication, a year, only 30 percent of patients achieved a normal level of sugar.

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To understand insulin resistance, it helps to understand a little about how insulin works and its role in the body. Insulin is an essential hormone created in the pancreas, which is involved in the metabolism of sugars in the body. Without it, we can not turn the food we eat into usable energy.

When we eat something, a lot of digested food is converted into glucose, the main energy source of the body. The pancreas then responds to blood sugar levels by secreting insulin in increasing the flow of blood. Most cells in your body contain insulin receptors that help insulin bind to the cell. Once insulin binds to the cell, activate other receptor sites, allowing glucose to enter the cell and provide energy for life.

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Dolphins have a mechanism that allows them to control levels of blood sugar. A study of dolphins revealed genetic clues that could help scientists find new treatments for type 2 diabetes in humans.

Scientists at the National Marine Mammal Foundation of America (NMMF) found that the bottlenose dolphin (Tursiops truncatus) is resistant to insulin, the hormone that regulates glucose levels in the blood-like people suffering type 2 diabetes .

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Obesity is not just a cosmetic problem: obesity for many years is often the cause of fat and metabolic disorders – as well as diabetes. A study of obese mice show that the interplay between hormones and proteins might be to blame.

The main cause for the development of metabolic disorders such as diabetes meilitus is a reduced response of cells to the hormone insulin. In particular, the cells in the muscles, liver and adipose tissue respond to the poor blood sugar-regulating hormone. A group of researchers from Austria has now examined more closely in this context, the interaction of insulin and fat cells.

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A great support for anyone with diabetes, the blood glucose self-regulation. It allows the patients on a personal security because they are always informed about the level of their current value and can respond quickly if needed. The patient can then have full control his illness and thus optimize treatment outcomes. For Type-1 diabetes, the blood glucose self-regulation already considered standard therapy, while in type-2 diabetes, most commonly used with insulin treatment. The application for type-2 diabetes without insulin treatment is controversial, especially in recent times.

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The treatment with the new diabetes drug is useful for certain diabetes patients. The Professional Association of diabetological specialist centers in North Rhine (BdSN) indicates that the active ingredient is wrote under certain conditions should be in order then to be able to contribute positively. “Patients on their current medication are well adjusted, but have no reason now to change the medicine,” said Dr. Ulrich Nühlen from BdSN. Liraglutide is in Germany and Britain since July on the market. The drug provides for that only increases with increased blood glucose, insulin is distributed. Thus, the drug not only lowers blood glucose levels but also reduces the risk of over-or hypo.

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Insulin therapy can be given earlier for the physically Diabetes Mellitus (DM) or type-2 diabetes who need, but not the last such therapy which is believed all along.

So far not a lot of insulin therapy is given to people with type-2 DM, because this therapy is considered as the last therapy or therapy for patients nearing death. As a result patients often refuse given insulin therapy, doctors also rarely want to give it, mostly because it considers the procedure is too complicated and troublesome because they have the patience to train the patient to inject insulin. And they are not.

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